Vaccine might allow Celiac disease patients to eat gluten

Plenty of testing is still needed

Doctors say this vaccine isn't an instant fix for celiac disease sufferers and it's unclear how many vaccines a patient would need.

Nexvax2, an immune system-modifying treatment, has received positive results during Phase 1 of trials. It has proven itself to be both safe and tolerable in adults with Celiac Disease.

Celiac disease is a condition in which people's immune systems react abnormally to gluten - a protein found in wheat, rye and barley - and this reaction damages the lining of the small intestine. It can damage the ability of the intestine to absorb nutrients and can lead to major health problems, including the development of other diseases like cancer or diabetes, according to the foundation.

A new vaccine may soon allow those who suffer from celiac disease to safely eat gluten.

Nexvax2 is now being tested in a phase 2 clinical trial in Australia that includes patients from the United States.

Yankees re-sign CC Sabathia to 1-year deal
The Cleveland Indians will listen to trade packages for both Corey Kluber and Carlos Carrasco , according to ESPN's Buster Olney. Cashman repeated he intends to trade pitcher Sonny Gray , just 15-16 since NY acquired him from Oakland in July 2017.

Accused mail bomber Sayoc to face new charges
A van linked to Sayoc has also emerged, showing heavy anti-Hillary stickers and pro-Trump stickers plastered all over its surface. One image showed the president standing on a tank with a rifle, complete with United States flag and fireworks.

Some iPhone X devices have touchscreen problems
The company said it only affects the original iPhone X, which has been superseded by the iPhone XS and XR released this autumn. Apple has announced two new replacement programs that impact the iPhone X and the 13-inch MacBook Pro without a Touch Bar.

The treatment - which consists of twice-weekly injections administered over a 16-week period - is made up of molecules called peptides, which elicit an immune response in patients with celiac disease. About 80 to 90 percent of those who have celiac disease also carry the immune recognition gene.

"Inadvertent gluten exposures can cause significant and long-term negative impacts on patient health".

A phase 2 clinical trial typically lasts around two years. After Phase 2 is deemed a success, it will undergo another round of clinical testing and then apply for approval at the U.S. Food and Drug Administration.

"This trial is important in establishing clinical proof-of-concept for a treatment that would provide benefit beyond that of the gluten-free diet", said Jason Tye-Din of the Royal Melbourne Hospital and principal investigator.

ImmusanT, the makers of Nexvax2, announced they've started phase-two clinical trials for the vaccine, which is created to protect people with celiac disease from inadvertent gluten exposure and, ultimately, could "allow patients to return to an unrestricted diet", ImmusanT CEO Leslie Williams said in a release about the clinical trials. "At ImmusanT, we are deeply committed to advancing Nexvax2 to protect celiac patients from the effects of inevitable gluten exposure", ImmusanT's CEO Leslie Williams said in a news release.

Related:

Comments

Latest news

Sears, Kmart to close 40 more stores, including last Kmart in Chicago
The additional closures follow an announcement last month that almost 150 other stores will close their doors this year. The new announcement shows Sears will no longer have a presence in Chicago , its longtime headquarters.

76ers put end to road struggles with 100-94 win at Indiana
After mysteriously losing his jump shot halfway through his rookie season, Markelle has looked much better so far in 2018. If the Sixers can hold off the Pacers in the closing minutes, they'll get their first road victory of the season.

Wilfried Zaha ruled out of Crystal Palace v Tottenham with hamstring problem
He is so obsessed with scoring that sometimes, when it is against him, he needs more freedom - not to be obsessed. However, there's no way that they can keep him out of Gareth Southgate's plans. "It's similar in Spain".

Beat Saber PS4 Gets Release Date
There's no word on a price just yet, but this should round out what has turned out to be an excellent year for PSVR. We don't have them yet, but we'll publish a story as soon as we pick up the Beat Saber Trophies .

Protesters Give Tucker Carlson's Wife a Fright
The protesters were doubling down and defending their protest after the ensuing backlash. Wednesday's incident prompted reactions from across the political spectrum.

United Kingdom must be able to withdraw from Irish backstop — Liam Fox
Michel Barnier cited the anti-EU British MEP Nigel Farage as a cautionary example at a conference of the centre-right European People's Party.

Leicester City To Wear Special Tribute Shirt Vs Burnley To Honour Srivaddhanaprabha
Srivaddhanaprabha was killed with four others in a helicopter crash outside Leicester's King Power Stadium on 27 October. His son Aiyawatt made the announcement in a souvenir programme for Saturday's Premier League game with Burnley.

Did gunman in latest United States mass shooting stop to make Instagram post?
The dead included 11 people inside the bar and a veteran sheriff's sergeant who was the first officer through the door. People escaped the bar by using chairs to break windows, while others reportedly sheltered inside the venue's toilets.

Nine dead in California wildfires, tens of thousands forced to flee
The dead were found in the same part of Paradise, the Butte County Sheriff's Office said. 'I'm driving through fire as we speak. The number of evacuations remains at 52,000 people so far, but the number of total structures destroyed has risen to 6,713.

Kuchar leads in Playa del Carmen, but Champ lurks
Park Sung Hyun shot a 67 and fellow South Korean Kim Sei Young had a 68 to put them both within five strokes of the lead. El Camaleon Golf Club is all about location - preferably the fairway - more than smashing it as far as possible.

Microsoft testing 'to-do' feature on Word
Microsoft Corp.is looking to streamline the workflow with a set of new productivity features for Word that it unveiled today. It may be the case that different people are required to complete tasks on the to-do list, so Microsoft also added mentions.

Fallout 76 beta locked to 63FPS on the PC because reasons
This issue will most likely be dealt with post-launch as Bethesda claims dealing with the stash size will "get easier over time". Our goal with voice chat being on by default is to highlight that the world is alive with real people, other players like you.

Age of Empires: Definitive Edition listed as available for Xbox One
There's no word on when the offer will end, so you'd better hurry on over to the Xbox Store to grab a copy for free. Crackdown 3 has a release window of February 2019 and will launch exclusively on Xbox One.

Japan’s Toshiba slashes 7,000 jobs
The announcement continued: "Unfortunately, it has not been possible to successfully conclude those negotiations ". Korea Electric Power Corporation had been earmarked as the preferred bidder to takeover but no deal has reached.

BMW previews M8, reveals a few engine details
BMW M has also increased the rigidity of the body structure, chassis components and chassis mounting. This enables the sedan to accelerate from 0-62 miles per hour (0-100 km/h) in just 3.3 seconds.

Other news