Hope in Africa as HIV vaccine shows promising results

Almost 80 million people are estimated to have been infected since the virus was first diagnosed in the early 1980s

To date, it's only one of five experimental HIV-1 vaccine concepts to make it this far in nearly four decades of the HIV pandemic.

The study results from these early trials have been published in the latest issue of the Lancet. Thousands of people are still contracting HIV every year in the US - an estimated 38,500 people became infected with the virus in 2015 alone, according to the Centers for Disease Control and Prevention's latest statistics. A safe and effective preventative vaccine is urgently needed to curb the HIV pandemic. "This ongoing trial might lead to further refinement of monkey models that can accelerate the preclinical evaluation of vaccine regimens".

In this study, the researchers aimed to evaluate mosaic adenovirus serotype 26-based HIV-1 vaccine candidates.

The authors also noted the relevance of vaccine protection in rhesus monkeys to clinical efficacy in humans remains unclear, and there was no definitive immunological measurement that was known to predict protection against HIV-1 in humans.

HIV-1 is the most common form of the virus, while HIV-2 is relatively uncommon and less infectious. However, people must take it regularly, i.e., sometimes daily, to protect themselves from the virus. Prep stands for pre-exposure prophylaxis.

Michelle Wolf Absolutely Nails Pro-Life Hypocrisy: They 'Do Not Care About Life'
She likened the phrase "pro-life" to "propaganda" terminology. "These people are anti-abortion, which means they are anti-woman. Trump has reportedly narrowed his short list of candidates down to four justices, all of whom sit on U.S.

The New Orange Is The New Black Trailer Just Dropped
It's jarring to see these women that we've followed for so many seasons in a new prison, immediately evoking a feeling of dread. The first official trailer teases major drama ahead as the women try to navigate complicated new dynamics.

One dead in helicopter crash in Virginia residential area
The accident took place in a residential area near the campus of William and Mary, which warned people to stay away from the area. Additionally, Burns said parts of the helicopter were strewn across the complex's parking lot and driveway.

Results showed that all vaccine regimens tested were capable of generating anti-HIV immune responses in healthy individuals and were well tolerated, with similar numbers of local and systemic reactions reported in all groups, most of which were mild-to-moderate in severity. This is not the case with the vaccine. The virus is able to mutate to avoid the attack of the human immune system, so we can't develop immunity to it.

Other researchers caution seeing this vaccine as the final solution to the virus. Therefore, it targets several different HIV strains. There are limitless HIV strains across the world. The participants all underwent a double-blind, random, placebo-controlled trial of what's being called the "mosaic" vaccine.

The study selected participants from around the world, notably those from the United States, Thailand, South Africa, Uganda, and Rwanda. They also tried the drug on 72 laboratory monkeys and proceeded to infect them with six injections of HIV like viruses.

A new vaccine to fight against HIV is giving medical professionals a bit of optimism, thanks to new research from Harvard. He is also Professor of Medicine at Harvard Medical School. Through this study, the researchers have found a new vaccine that seems to be appropriate and safe and induces an immune in human beings as well as the rhesus monkeys. "Moreover, the vaccine provided 67 percent protection against viral challenge in monkeys".

Susan Buchbinder, MD, of the University of California San Francisco, one of the co-chairs of the ongoing phase IIb efficacy trial for this vaccine, explained that the results of the non-human primate study were used to help select the most appropriate candidate for the vaccine in humans.



Latest news

Gulbis tops Zverev at Wimbledon
A win in last 16 could see him potentially face 12-time Grand Slam champion Novak Djokovic in the quarter-finals. On Monday, Gulbis will face No. 24 seed Kei Nishikori of Japan, who was the runner-up at the 2014 U.S.

Reuters journalists charged under Myanmar Official Secrets Act
Wa Lone, 32, and Kyaw Soe Oo, 28, who pleaded not guilty after being charged on Monday, were detained late previous year . He said four witnesses will be called for the reporters' defense, including their driver on the night of the arrest.

After Losing Everything, Husband Proposes To His Wife Again
And their home burnt down in the recent Californian wildfires - taking Laura's wedding and engagement rings with it. Ishu Rao found the charred rings amid the ashes after figuring out where the kitchen sink was by looking for pipes.

Niantic’s Ingress is getting an anime series on Netflix
Ingress is coming to Netflix this fall with Niantic announcing a new anime based on the augmented reality game. We want to make sure people can make their way through that and get to the actual gameplay.

Fans ask Microsoft to make Surface Phone a reality
In a lot of ways, re-entering the smartphone industry with a powerful productivity device would be a strategic move for Microsoft. The petition, on Change.org, has already gained over 6,300 signatures in just over a day of being live.

Kensington Palace announces Prince Louis' godparents
James's Palace in London , Prince George was dressed up in the newly made replica of the classic Victorian christening gown. George, four, and three-year-old Charlotte held William's hand, as a sleeping Louis was carried into the chapel by Kate.

Tab Hunter, Star of Damn Yankees!, Dead at 86
In June it was announced that JJ Abrams and Zachary Quinto are producing the movie "Tab & Tony" about the secret love affair. I was just brought up that way. "I think it was easier with the movie because it was quite a few years later after the book".

Son of Former South African President Zuma Charged With Corruption
He is also due in court on Thursday on culpable homicide charges over a deadly vehicle crash in 2014. Jonas revealed how he was offered a bribe to take the job of finance minister.

Harvey Weinstein arrives at Manhattan court to face predatory sexual assault charge
Weinstein's CT home for the past 23 years, she said, should no longer an option because records show that it has been sold. Courthouse guards told people arriving for jury duty to wait or use a different entrance as Weinstein arrived on Monday.

England fans celebrate World Cup win over Sweden at IKEA
The last time England reached the semis was in 1990 in Italy, when they lost out to Germany in a penalty shootout. We've been playing well, we're learning and we're all enjoying it.

Roger Federer eases past Mannarino into Wimbledon quarter-finals
Rodina, through to the fourth round of a Grand Slam for the first time, was 0-15 against top-20 ranked opponents before the win. Keys also came up short with a comeback attempt after fighting back from a set and two breaks down, losing 7-5, 5-7, 6-4.

British foreign secretary Boris Johnson resigns amid Brexit fallout
European Council President Donald Tusk said it was unfortunate the whole "idea of Brexit has not left together with David Davis". A broker looks at a graph on his computer screen on the dealing floor at ICAP in London , Britain January 3, 2018.

Polar's fitness app exposed its users' sensitive location details
However, with enough digging, Polar's tracking info also exposes its users' names and home addresses. This included the location details of soldiers and secret agents .

The last straw? Starbucks pledges to eliminate plastic straws globally by 2020
The brewer is phasing out plastic, one-time-use straws, because of material waste and danger to aquatic sea life they can cause. A number of local governments have recently passed legislation restricting the use and distribution of plastic straws.

West Nile virus positive mosquitoes detected in Boston
West Nile virus is an infectious disease that was first introduced to the United States in 1999. On June 28, mosquitoes in Suffolk tested positive for the West Nile Virus and EEE.

Other news