Jacksonville Jaguars @ San Francisco 49ers: Jags finding their stride as predators

49ers Inactives Garrett Celek available to play Jaguars missing top-2 WRs

The Jaguars will secure the division crown with a win or tie against the 49ers, or if the Titans tie or lose to the Los Angeles Rams.

Defensive end Dante Fowler Jr. was called for holding later on the drive, which ended with 49ers quarterback Jimmy Garoppolo throwing five yards to wide receiver Trent Taylor for a 30-19 lead the 49ers never fully relinquished.

The Jaguars (10-4) clinched their first playoff berth since the 2007 season after defeating the Houston Texans.

- Running back Matt Breida iced the win with a 30-yard touchdown run with 84 seconds remaining. The 49ers' quarterback connected with tight end George Kittle on a eight-yard touchdown completion.

BENGALS 26, LIONS 17: Giovani Bernard ran for 116 yards and a clinching touchdown in the closing minutes, sending Cincinnati (6-9) to a victory at home that eliminated Detroit (8-7) from playoff contention and gave Marvin Lewis a good moment in what was possibly his final home game as Bengals coach.

Before they even stepped onto the field in Santa Clara, the Jacksonville Jaguars knew they had locked up the AFC South title - and they played like in a pathetic 44-33 loss to the San Francisco 49ers.

Garoppolo and the 49ers got off to an extremely hot start and, after two impressive scoring drives and a pick-six by Dontae Johnson, were 16-0 up within a blink of an eye.

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Garoppolo threw sidearm just before Jacksonville cornerback Aaron Colvin got to him. At one point this season the team was winless, now they're in a position to be deemed "the rich getting richer" with a Top 10 draft pick and $115 million to spend on new talent. But his first half ended on a sour note.

Garoppolo's pass intended for Kendrick Bourne fluttered as he was hit by Jaguars pass-rushers Calais Campbell and Yannick Ngakoue.

Blake Bortles also had a rough day, but this loss was on the defense - they got pushed around early and never really recovered.

The 49ers extended their lead when Robbie Gould kicked a 27-yard field goal. In his time with the Niners, he's 100-of-145 for 1,268 yards with five touchdowns and three interceptions for a passer rating of 98.9.

Bortles, however, couldn't avoid his first three-interception game since 2016 against Baltimore Ravens. He evaded pressure (on the few times the Jaguars got some), confused the Jaguars on bootlegs and found his second and third reads. But the Jaguars blocked the extra point attempt and Colvin returned it for two points. The turn of events meant the 49ers carried a 16-2 lead after the play. Jimmy Garoppolo sneaked the ball in for the first touchdown of the game and the first rushing touchdown of his career.

TURNING POINT After the Jaguars went on a 19-point spree, the 49ers stopped that momentum and used Williams first-career interception - a remarkably athletic one - to produce their go-ahead touchdown drive.

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