Saints RB Daniel Lasco taken off field by ambulance

NFL betting tips: Free betting tips and odds for Sunday night as Buffalo host New Orleans

Peterman's debut: With 4:52 left in the game and the Bills trailing by 37 points, rookie Nathan Peterman came in at quarterback for Tyrod Taylor. The streaking Saints, winners of seven-straight games, took a dominate 47-10 win over the Bills.

-New Orleans would get a field goal before the end of the half as Will Lutz put a 23-yard attempt up and through for a 17-3 lead at the half.

The Bills were hoping their Week 9 loss to the Jets was an aberration.

-A pass that went off the hands of Charles Clay deep in Buffalo territory was intercepted by Sheldon Rankins and returned to the Bills three-yard line.

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However, it was perfectly reasonable for fans to expect something better out of McDermott's defense as it returned home, where the Bills had a 4-0 record entering Sunday.

They now revert to an underdog role as they play host to the streaking Saints, who have won six on the spin and hold the second seeding currently in the NFC, and will benefit from a start on the spread. Brees did have a rushing score, which is how the Saints' flexed their muscle against the Bills. As a team, New Orleans averaged six yards-per-carry.

In winning their seventh game in a row, the 7-2 Saints had two rushers with more than 100 yards - Mark Ingram (131) and Alvin Kamara (106). The Saints' 298 rushing yards were the eighth-most against Buffalo in their franchise history and most since 2012, when the Seattle Seahawks ran for 311. Last season, the Bills allowed three teams to run for over 200 yards, but none for 300.

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